Hypercholesterolemia. Cholesterol metabolism : Cholesterol is readily oxidized to form Oxysterols. What is cholesterol? Cholesterol can be oxidized in three ways as follows : Autooxidation, Secondary Oxidation and Cholesterol-metabolizing Enzyme Oxidation. The excess cholesterol produced in this way activates acetyl-CoA cholesterol acyl-transferase (ACAT), which re-esterifies cholesterol into cholesterol esters that can be deposited as lipid droplets or mobilized again to where it is needed. Disturbances in cholesterol metabolism cause various diseases. Your body needs some cholesterol to make hormones, vitamin D, and substances that help you digest foods. Its overall effect is … As the body requires cholesterol, it may be secreted by the liver. Learn about prevention and treatment of high cholesterol, triglycerides, ldl, hdl, athersclerosis, arteriosclerosis, hypercholesterolemia, bad cholesterol, reducing cholesterol, cholesterol screening, cholesterol tracker, recipes and preventing high cholesterol. After a meal, cholesterol in the diet is absorbed from the small intestine and metabolized and stored in the liver. Cholesterol content in the bloodstream is regulated by the liver. Cholesterol has a bad reputation, thanks to its well-known role in promoting heart disease. Excess cholesterol in the bloodstream is a key contributor to artery-clogging plaque, which can accumulate and set the stage for a heart attack. Flow of Presentation What is Lipids – Rajesh Conversion of VLDL to LDL – Kuldip Fatty acid oxidation – Zalak Oxidation of odd carbon - Pravin Ketone Bodies – Sachin Metabolism of Cholesterol & functions – Kishore Cholesterol Biosynthesis – Gulab Regulation of Cholesterol – Aadesh Degradation of Cholesterol … A cholesterol test will measure the total cholesterol in your blood, and your total cholesterol levels are made up of a combination of your LDL, HDL, and VLDL (very low density lipoprotein, another "bad" cholesterol) levels. Metabolic disease - Metabolic disease - Disorders of lipid metabolism: Lipids are large, water-insoluble molecules that have a variety of biological functions, including storing energy and serving as components of cellular membranes and lipoproteins. The science behind the GOOD and BAD cholesterol. However, if concentrations in the blood get too high, it … CHOLESTEROL PRESENTED BY:-SILENT KILLERS 2. Cholesterol is a waxy, fat-like substance that's found in all the cells in your body. Cholesterol transport and pathways, drugs used for treatment of atherosclerosis. A total cholesterol score of 200 mg/dL or lower is considered optimal. However, the role of cholesterol … Cholesterol is both good and bad. The American Heart Association explains how cholesterol affects the heart. But cholesterol is necessary for the creation of hormones, vitamin D, and enzymes needed for digestion. Cholesterol metabolism 1. HDL metabolism is complex, but one role of HDL is to obtain cholesterol from peripheral tissues and other lipoproteins and transport it to where it is needed most—other cells, other lipoproteins (using cholesteryl ester transfer protein [CETP]), and the liver (for clearance). Your body makes all the cholesterol it needs. Bundles called lipoproteins carry cholesterol throughout the body. At normal levels, it is an essential substance for the body. 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